Clozapine-Related Agranulocytosis

4 April 2015
Research proposal to determine role of drug and/or contaminant in adverse reaction from psychotic patients.

Is clozapine-related agranulocytosis the result of the medication itself or due to an as yet unconfirmed report of a contaminant in the medication which has now been removed by the drug’s manufacturers? To determine the answer to this question, the proposed research will compare incidence of precipitant agranulocytosis in a sample of 50 patients beginning clozapine treatment (all with a past history of clozapine-related agranulocytosis which is now cured).

Literature Review
To place the proposed research in the context of the existing work in the field, this section of the proposal presents a comprehensive review of the literature. The first section of the review presents a general discussion of clozapine-induced..

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Clozapine-Related Agranulocytosis. (2015, Apr 23). Retrieved December 6, 2019, from
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