Hemophilia Essay Research Paper Hemophilia Hemophilia is

8 August 2017

Hemophilia Essay, Research Paper

Hemophilia Hemophilia is a genetically inherited hemorrhage upset which is caused when one of the plasma proteins ( needed to coagulum ) is losing or abnormally formed in the blood. The word Hemophilia comes from the Latin word hemo, intending blood and the word affection, significance: holding a inclination towards. Knowledge of haemophilia has been around since scriptural times ( due to the age of haemophilia it is unsure who the exact laminitis of the disease is ) but it wasn & # 8217 ; t until the 1960 & # 8217 ; s that scientists began to do new progresss towards calculating out what haemophilia was. There are two types of haemophilia: hemophilia A or factor VIII lack, and haemophilia B or factor IX lack. Hemophilia A is more common than hemophilia B with 85 % of those affected by haemophilia holding it. A individual with haemophilia does non shed blood harder or faster than a normal individual would when injured, but they bleed longer because their blood is unable to organize a house coagulum.

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Small cuts are usually non a job, but sometimes shed blooding in the articulations occurs due to a individual & # 8217 ; s organic structure growing. This consequences in swelling of the affected articulation and extreme hurting when the joint or musculus is moved. It is reported that one in ten thousand males get hemophilia A. It has been calculated that worldwide there are about 350,000 people with terrible or moderate haemophilias, although haemophilia B is 5 times less common that hemophilia A. All races, faiths, and economic groups are affected by haemophilia. Hemophilia is a hemorrhage upset which is inherited genetically. Due to the form of heritage, the upset by and large affects males merely. About one tierce of hemophilia instances come with a old household history. Womans with a haemophilic cistron are called bearers while work forces are either haemophiliac or normal. A girl of a female parent who is a bearer and a male parent who is normal has a 50 % opportunity of being a bearer herself. A boy of the same female parent and male parent has a 50 % opportunity of holding hemophilia. Most of the clip bearers are non affected by the disease, but sometimes there are minimum symptoms. Many times hemophilia is hidden for many coevalss if no affected males are born. Therefor the haemophilic cistron is carried through many coevalss of females who, because they have

one X chromosome that is normal, do not suffer from the disease themselves. Other cases may have no family history, which would mean that the change in the X chromosome is a new one. This is called a mutation of the gene. Hemophilia has played an important role in Europe’s history, for it suddenly cropped up in the children of Great Britain’s Queen Victoria. It became known as the “Royal disease” because it spread to the royal families of Europe through Victoria’s descendants. Hemophilia first appeared in Victoria’s family in her eighth child, Prince Leopold, Duke of Albany. Throughout his short life, Leopold had suffered severe hemorrhages, and always was described as “very delicate.” Leading the life of a normal youngster was impossible for Leopold because any cut or bump could lead to death and it had been necessary to keep him always under strict surveillance. However, in spite of all protection, Prince Leopold died at the age of thirty-one, as a result of a minor fall. The disease then took off from there in the royal family. It was either given to a male descendant (causing him to be a hemophiliac) or a female descendant (causing her to be a carrier). The present-day royal family is unaffected by the disease. The treatment of hemophilia involves the simple injection of the deficient factor (usually found in blood derivatives or factor concentrates) directly into the individual’s vein. This will either prevent bleeding, or minimize the effects so that the patient remains free of disability and problems. If treatment is delayed the bleeding continues, causing more tissue damage, and eventually a permanent disability. If a hemophiliac has severe bleeding or surgery, a continuous blood replacement therapy is applied to maintain healthy levels of the clotting factor. Untreated, hemophilia is a lethal disease. At the beginning of this century the life expectancy of someone with hemophilia was less than fifteen years. Today, with good treatment, and a fair amount of knowledge, a male’s life expectancy with hemophilia is only ten years less than a normal male’s life. This is only the beginning of treating hemophilia. With the recent genetic technological advances taking place, there is no telling what treatment or prevention methods scientists will think of next.

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