Liquid Chromatography

2 February 2017

What is meant by polarity of molecules? What causes differences in polarity? The polarity of molecules is the slight charge associated with a covalent molecule due to the uneven sharing of electrons. Electrons, being the source of mobile charge within atoms, can be attracted to one of a pair of atoms within a bond, due to a greater of affinity of electrons by an element compared to another. With an excess of this negative charge carriers, one side of the molecule becomes more negative than the other, thus creating two distinct “poles”: a positive end and a negative one.

Differences in polarity are due to the greater affinity for electrons by certain elements contrasted with others, such as oxygen over hydrogen. 2. In discussing solubility, the rule “like dissolves like” is frequently used. What does this mean? This term means that: * Solvent and solute have similar/compatible structures: causes solute to readily dissolve in the solvent * Example: Water (H2O) participates in hydrogen and so does methanol CH4O; thus, methanol readily dissolves when placed in water 3. Draw the structural formula of isopropyl alcohol.

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